You can use The US Road Closure Form to submit any closure longer than a few days.
The South Carolina Department of Transportation maintains a website regarding road closures throughout the state. Please use this link to access a list of closures by county. The SCDOT also publishes a map of closures for DOT maintained (S numbered) roads.
We also maintain a South Carolina Road Closures spreadsheet of the closures in the state. If you submit a closure, please add some or all of the information to that page.